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Cardiovascular Panel: BNP OEM kit Adopting Chemiluminescence assay platforms

Cardiovascular Panel: BNP OEM kit Adopting Chemiluminescence assay platforms

Brain Natriuretic Peptide (BNP) is applied for auxiliary diagnosis, risk stratification, and prognosis assessment of heart failure, as well as the differential diagnosis of cardiogenic and non-cardiogenic dyspnea.

BNP OEM kit utilizes a two-antibody sandwich immunoassay and is applicable to chemiluminescence platforms. Specific monoclonal antibodies target distinct epitopes on N-terminal and C-terminal regions of the BNP molecule to capture plasma BNP, delivering high sensitivity and exceptional specificity. Calibrated with high-purity recombinant BNP, the assay provides accurate, reliable, and stable quantitative results. Serving as a gold-standard biomarker for heart failure management, it supports early identification, clinical triage, and dynamic therapeutic monitoring of cardiac dysfunction.

 

Bulk reagents are available with matching raw materials. 

 

 

 

 

 

 

 

 

  • Brand :

    QYM,SURFTECH
  • Item No :

    BNP-1
  • Order(MOQ) :

    On request
  • Payment :

    T/T
  • Product Origin :

    China
  • Color :

    R1 should be a colorless to pale yellow transparent liquid; R2 should be a milky white suspension.
  • Shipping Port :

    Hefei or other ports
  • Lead Time :

    On request
  • Weight :

    On request

BNP OEM reagent

Product Specifications

  

Product Name BNP OEM reagent (chemiluminescence platforms)
Application: It is applied for auxiliary diagnosis, risk stratification, and prognosis assessment of heart failure, as well as the differential diagnosis of cardiogenic and non-cardiogenic dyspnea.

Assay Principle:

Two-antibody sandwich immunoassay 

Sample Type: 

Serum / Plasma

Calibrator Component: 

Recombinant BNP

Sample volume

50 μL

Limit of detection

15 pg/mL

Measuring range

15 pg/mL ~ 5000 pg/mL

Reference interval

100 pg/mL

Traceability

Abbott

Precision

Within-run ≤5%; Between-run ≤8%

Interfering Substances

Bilirubin <20 mg/dL; Triglycerides <3000 mg/dL; Biotin ≤30 ng/mL

Method comparison

Correlation coefficient (R²) ≥0.90 in large sample study vs Abbott assay

Hook Effect Concentration

100000 pg/mL

Package Size

on request

Storage/Shipping Store sealed and protected from light at 2 °C to 8 °C
Shelf Life 12 months
    

 

Product Advantages

1.Sensitivity complies with requirements

2.Good correlation across linear range

3.Outstanding precision at all concentrations

4.Stable long-term storage (heat resistance verified)

 

5.Strong correlation vs international mainstream brands in clinical comparison

 

 

                   Sensitivity Analysis                        Batch precision test                       Linear Range Validation            

           

 

      Clinical comparison                                    Thermal damage test   

   

 

 

 

Application Scenarios

 

 

Brain Natriuretic Peptide (BNP) is applied for auxiliary diagnosis, risk stratification, and prognosis assessment of heart failure, as well as the differential diagnosis of cardiogenic and non-cardiogenic dyspnea.

 

--------------占位---------------

FAQ

What is the reportable range and the upper limit for the high-dose Hook effect in acute heart failure?

The measuring range covers 15 pg/mL ~ 5000 pg/mL . The formulation prevents high-dose Hook effects up to 100000 pg/mL, eliminating false negatives in severe acute decompensated heart failure.

 

How well does it correlate with clinical reference platforms (e.g., Abbott )?

 Excellent agreement. Clinical trials across heart failure cohorts yield R^2 > 0.95  against benchmark chemiluminescence BNP assays, ensuring identical clinical rule-out/rule-in cut-offs.

 

 

 
 
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