HBP test

Heparin-Binding Protein (HBP), a neutrophil-derived granule protein, serves as an early diagnostic biomarker for infectious diseases, particularly severe bacterial infections. Serum/plasma HBP levels rise significantly in bacterial infections, whereas non-bacterial infections do not induce such an elevation. Heparin-Binding Protein (HBP) is applied for the early identification, risk stratification, and prognosis assessment of severe bacterial infections and sepsis, as well as the differential diagnosis of acute inflammatory conditions and localized infection-induced vascular leakage. HBP OEM kit utilizes a two-antibody sandwich immunoassay and is applicable to chemiluminescence platforms. Specific monoclonal antibodies target distinct structural epitopes on the HBP molecule to capture plasma or serum HBP, delivering high sensitivity and exceptional specificity without cross-reactivity to other neutrophil granule proteins. Calibrated with high-purity recombinant HBP antigen, the assay provides accurate, reliable, and stable quantitative results. Serving as an early-warning biomarker for acute vascular leakage and organ failure, it supports timely clinical intervention, triage in emergency and intensive care units (ICU), and dynamic therapeutic efficacy monitoring in severe infectious diseases.   ★Bulk reagents are available with matching raw materials.