Pepsinogen I (PGI) is applied for the screening, risk stratification, and auxiliary diagnosis of chronic atrophic gastritis and gastric cancer, as well as the non-invasive evaluation of gastric mucosal secretory function and gastric body atrophy.
PGI OEM kit utilizes a two-antibody sandwich immunoassay and is applicable to chemiluminescence platforms. Specific monoclonal antibodies target distinct structural epitopes on the PG I molecule to capture serum or plasma PG I, delivering high sensitivity and exceptional specificity without cross-reactivity to Pepsinogen II (PG II). Calibrated with high-purity recombinant PG I antigen, the assay provides accurate, reliable, and stable quantitative results. Serving as a primary non-invasive biomarker for gastric acid secretory capacity, when combined with PG II and the PGI/PGII ratio (PGR), it supports early identification of gastric mucosal atrophy, non-invasive gastric cancer risk stratification, and clinical therapeutic monitoring.
★Bulk reagents are available with matching raw materials.
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